Proton Activated Channels uncover how some can thrive at altitude.

A 2015 manuscript suggests that Ca2+ entry via TrpV1 channels can activate TMEM16A channels in pain neurons.

Wase Tembo attended the 2018 Physics of Living Cells Summer School.  Below she answered some questions about her experience!

Katie reflects on her experiences in the 2017 Frontiers in Reproduction course at Woods Hole

Three excellent undergraduate researchers reflect on their time in the Carlson lab.

Erratic heart beats and the KCNE channel subunit

Targeting TMEM16a channels may be useful for treating cystic fibrosis

A new manuscript describes the how proteins are phosphorylated during egg activation.

A new report indicates that oxytocin activates the same channels as chili peppers

The Zn2+ released by eggs at mammalian fertilization, may act as a polyspermy block.

It turns out that the way we talk about science is changing, and fast!  

A recent manuscript from Lily Jan's lab attempts to uncover the pore lining residues of the Ca2+-activated Cl- channel TMEM16a.

What sperm factor activates Ca2+ oscillation and the resumption of meiosis in the egg?

In 2005, Rosario Maroto and coworkers (from the lab of Owen Hamill) at the University of Texas Medical Branch identified a component of the vertebrate mechanosensitive cation channel (MscCa) as the canonical transient receptor potential channel 1 (TRPC1).

Another Cl- channel related structure published!  Here, a structure for a member of the Bestrophin (BEST) family has been resolved by Wayne Hendrickson and colleagues from Columbia.

The structure for a member of the TMEM16 family has been resolved by Raimund Dutzler and colleagues from Zurich (pdb id: 4WIS).

Jie Zheng and his postdoc Fan Yang, published a new manuscript reporting intrinsic temperature sensitivity in voltage gated K+ channels, including the Shaker channel.

Recently, Sharona Gordon posted a thought-provoking article on on the lack of gender equality in physiology.